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Korea Radio-Isotope Center for Pharmaceuticals

Welcome to Korea Institute Of Radiological & Medical Sciences.

Support disease animal models based on optical imaging

Disease model Type
Stereotactic tumor mouse model Brain, lung, liver, prostate, breast
Metastatic tumor mouse model Experimental, Osteoblastic
User-customized xenograft model Human or murine cancer cell lines
  • Stereotactic tumor mouse model

  • Metastatic tumor model

Support efficacy evaluation using bioimaging

Bioimaging equipment
Small animal PET/CT Small animal Micro CT
Large animal PET/CT Small animal optical imaging
Small animal MRI (9.4T) PET insert for small animal PET/MR imaging
Small animal SPECT/CT
  • Small animal PET/CT

  • Small animal MRI (9.4T)

Support ex vivo efficacy evaluation of Radioisotope-labeled Compounds

Biodistribution Study
Confirmation of accumulation of RI-labeled compounds in each organ over time
QWBA
Distribution and quantification analysis of RI-labeled compounds in experimental animals
Pathological analysis on the blood and tissue
Conduct biochemical blood analysis and histological tissue analysis

Support in vitro efficacy evaluation of Radioisotope-labeled Compounds

  • Cellular uptake assay
  • Cell binding assay
  • Serum stability assay
  • Cytotoxicity assay